Collagenase treatment of Dupuytren’s contracture using a modified injection method
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چکیده
منابع مشابه
Collagenase treatment of Dupuytren’s contracture using a modified injection method
BACKGROUND AND PURPOSE Treatment of Dupuytren's contracture (DC) with collagenase Clostridium histolyticum (CCH) consists of injection followed by finger manipulation. We used a modified method, injecting a higher dose than recommended on the label into several parts of the cord, which allows treatment of multiple joint contractures in 1 session and may increase efficacy. We studied the occurre...
متن کاملPhalangeal Fracture During Attempted Dupuytrens Release Following Clostridial Collagenase Injection: Case Report
Introduction Dupuytren's disease can be a challenging condition for both patients and surgeons. Injectable collagen clostridium histolyticum was approved for clinical use by the Food and Drug Administration in 2010. A number of side effects have been described. In this case report, we present a complication of a proximal phalanx fracture which occurred during attempted release post injection. T...
متن کاملComparative Effectiveness of Needle Aponeurotomy and Collagenase Injection for Dupuytren’s Contracture: A Multicenter Study
BACKGROUND Although the efficacy of collagenase clostridium histolyticum (CCH) injections has been demonstrated by randomized clinical trials, the relative effectiveness of CCH remains uncertain. Our aim was to compare the outcomes of CCH with those of percutaneous needle aponeurotomy (PNA) in daily clinical practice. METHODS We analyzed data from patients undergoing PNA or CCH between 2011 a...
متن کاملIntra-articular collagenase injection increases range of motion in a rat knee flexion contracture model
Objectives A knee joint contracture, a loss in passive range of motion (ROM), can be caused by prolonged immobility. In a rat knee immobilization flexion contracture model, the posterior capsule was shown to contribute to an irreversible limitation in ROM, and collagen pathways were identified as differentially expressed over the development of a contracture. Collagenases purified from Clostrid...
متن کاملPalmar fasciectomy after collagenase Clostridium histolyticum injection for Dupuytren’s contracture: A case report.
We present a case of successful salvage fasciectomy after initial collagenase Clostridium histolyticum (CCH) injection for the treatment of Dupuytren’s contracture. We did not find any remarkable scarring around the Dupuytren’s cord and nodule three and a half years after the initial CCH injection. Pathological findings revealed the previously ruptured cord and partial continuity of the collage...
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ژورنال
عنوان ژورنال: Acta Orthopaedica
سال: 2015
ISSN: 1745-3674,1745-3682
DOI: 10.3109/17453674.2015.1019782